Head of Translational Medicine

TRANSLATIONAL MEDICINE

JOB DESCRIPTION

We are seeking an experienced scientific leader for our translational medicine team. Successful candidates will play an integral role in guiding clinical development by innovating and validating biomarker assays for patient stratification, pharmacodynamics, and surrogate efficacy.

RESPONSIBILITIES

  • Envisions and leads the full potential of the single cell-based readouts, from target identification to precision medicine-based clinical applications.
  • Charts the course for pushing the current boundaries of single cell technologies and their clinical applications.
  • Devises and leads the translational efforts for multiple oncology, immunology, and in areas such as autoimmune programs in preclinical/clinical development.
  • Delivers impactful experimental design, data, and translational insights that inform patient selection, pharmacodynamic/response biomarkers, and mechanisms of drug resistance.
  • Leads an internal team and leverages CROs/academic collaborators to effectively deliver on program goals.
  • Maintains high-functioning and synergistic cross-functional relationships across the Celsius organization.
  • Serves as a nucleus for the formation of the future Development organization.
  • Communicates science and strategy effectively in a variety of internal and external settings.
  • Hands on leadership approach

QUALIFICATIONS

  • D. with at least 15+ years of post-graduate oncology, immunology, or autoimmune experience with focus on translational research.
  • Demonstrated success as a lead scientist who has executed on advancing novel scientific discoveries that impacted the course of clinical development for innovative therapeutic(s).
  • Breadth of experience across multiple indications developing assays for disease tissues and/or surrogate tissues (e.g., PBMC, plasma) to derive PK/PD/efficacy relationships.
  • Experience with quantitative measurements of protein, DNA, and RNA in multiple tissues.
  • Experience with IND-enabling studies is desired.
  • Prior experience managing and mentoring direct reports and working with international CROs.
  • Exceptional verbal and written communication and interpersonal skills to work across functions.
  • Excellent organizational and time-management skills and demonstrated ability to lead cross-functional collaborations, including managing relationships with academic collaborators and CROs.
  • Desire and capacity to participate in a dynamic and fast-paced research setting.
  • Recognized scientific innovation and accomplishment evidenced by strong record of publications and conference presentations.
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